Description

2-Furancarboxylicacid,Tetrahydro-5-Hydroxy-,Methylester,(2R-Trans)-(9Ci) is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex, stereochemically defined molecules, offering researchers and manufacturers precise control over molecular architecture. Industries involved in pharmaceutical development, agrochemical research, and fine chemical manufacturing require this specific enantiomer to ensure the efficacy and safety of their final products.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing central nervous system (CNS) agents and other therapeutic compounds.
• Agrochemical Synthesis: Used in the research and production of advanced, enantiomerically pure pesticides and herbicides to enhance specificity and reduce environmental impact.
• Fine Chemical Production: Serves as a versatile precursor for creating complex fragrance molecules, flavors, and other specialty chemicals where stereochemistry is crucial.
• Academic & Industrial Research: A valuable reagent in methodological development for asymmetric synthesis and catalysis studies within R&D laboratories.
• Material Science Precursor: Potential application in synthesizing chiral ligands for catalysts or monomers for specialized polymers.

Basic Information

Product Name	2-Furancarboxylicacid,Tetrahydro-5-Hydroxy-,Methylester,(2R-Trans)-(9Ci)
CAS No.	174689-93-1
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(2R)-Tetrahydro-5-hydroxy-2-furancarboxylic acid methyl ester; Methyl (2R)-tetrahydro-5-oxo-2-furoate; (R)-(-)-Tetrahydro-5-oxo-2-furancarboxylic acid methyl ester; 5-Hydroxytetrahydro-2-furancarboxylic acid methyl ester, (2R-trans)-; Tetrahydro-5-hydroxy-2-furancarboxylic acid methyl ester, (2R-trans)-; (2R,5S)-5-Hydroxytetrahydrofuran-2-carboxylic acid methyl ester; A chiral γ-lactone derivative.
EINECS	Contact for details

Quality Control

Our 2-Furancarboxylicacid,Tetrahydro-5-Hydroxy-,Methylester,(2R-Trans)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.