Description

2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2R-Cis)-(9Ci) is a chiral, high-purity chemical intermediate of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for producing enantiomerically pure compounds with specific biological activity. This product is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries, particularly for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in neurological and metabolic disorder research.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereocenters.
• Flavor & Fragrance Industry: Serves as a starting material for the development of novel, complex aroma chemicals with specific olfactory profiles.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where enantiopurity affects efficacy and environmental impact.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the development of new synthetic pathways.
• Specialty Polymer Modification: Can be used to introduce functional furan-based moieties into polymer chains for specialized material properties.

Basic Information

Product Name	2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2R-Cis)-(9Ci)
CAS No.	174689-92-0
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(2R,5S)-5-Methoxy-2-tetrahydrofuroic acid methyl ester; Methyl (2R,5S)-5-methoxy-2-tetrahydrofuroate; Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester, (2R-cis)-; (2R-cis)-Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester; cis-5-Methoxy-2-tetrahydrofuroic acid methyl ester; (2R,5S)-Tetrahydro-5-methoxy-2-furoic acid methyl ester; (2R,5S)-Methyl 5-methoxytetrahydro-2-furoate
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including Chiral HPLC and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with every shipment. We support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.