Description

2H-Pyran-3,4-Diamine,Tetrahydro-2-Methoxy-,[2S-(2Alpha,3Beta,4Beta)]-(9Ci) is a chiral, stereochemically defined diamine derivative of a tetrahydro-2-methoxypyran scaffold. This compound is a high-value pharmaceutical intermediate and a versatile chiral building block for the synthesis of complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Asymmetric Synthesis: Serves as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its rigid, functionalized pyran ring structure.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for exploring new synthetic methodologies and constructing heterocyclic compound libraries.

Basic Information

Product Name	2H-Pyran-3,4-Diamine,Tetrahydro-2-Methoxy-,[2S-(2Alpha,3Beta,4Beta)]-(9Ci)
CAS No.	174647-16-6
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	(2S,3R,4R)-3,4-Diamino-2-methoxytetrahydro-2H-pyran; (2S,3R,4R)-2-Methoxy-3,4-diaminotetrahydropyran; Tetrahydro-2-methoxy-2H-pyran-3,4-diamine, (2S,3R,4R)-; 2H-Pyran-3,4-diamine, tetrahydro-2-methoxy-, (2S,3R,4R)-; 174647-16-6; (2S,3R,4R)-3,4-Diamino-2-methoxytetrahydro-2H-pyran; (2S,3R,4R)-2-Methoxy-3,4-diaminotetrahydropyran
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess and NMR for structural confirmation, to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We support cGMP compliance for pharmaceutical applications, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.