Description

6-Trifluoromethylpyridazin-3(2H)-One is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs) due to the unique physicochemical properties imparted by the trifluoromethyl group. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with enhanced metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the design of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved biological activity.
• Material Science Research: Serves as a building block for creating advanced organic materials, such as ligands for catalysis or components for electronic materials.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	6-Trifluoromethylpyridazin-3(2H)-One
CAS No.	174607-36-4
Molecular Formula	C5H3F3N2O
Molecular Weight	164.09 g/mol
Synonyms	3(2H)-Pyridazinone, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-3(2H)-pyridazinone; 6-(Trifluoromethyl)pyridazin-3(2H)-one; 6-Trifluoromethyl-3(2H)-pyridazinone; 6-Trifluoromethyl-3-hydroxypyridazine; 3-Hydroxy-6-trifluoromethylpyridazine; 2H-Pyridazin-3-one, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethylpyridazin-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.