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1,1'-Bis((R)-(Dimethylamino)(Phenyl)Methyl)Ferrocene CAS NO 174589-08-3


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CAS No.:174589-08-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,1'-Bis((R)-(Dimethylamino)(Phenyl)Methyl)Ferrocene is a chiral ferrocene-based ligand, a sophisticated organometallic compound prized for its role in asymmetric synthesis. This compound matters because it provides a highly effective and selective framework for catalyzing critical carbon-carbon bond-forming reactions, enabling the production of enantiomerically pure intermediates. It is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries who require high-performance, tunable catalysts for creating complex chiral molecules.

Application

  • As a chiral ligand in asymmetric catalysis, particularly for palladium-catalyzed reactions.
  • Key component in the synthesis of enantiomerically pure pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
  • Use in asymmetric hydrogenation and cross-coupling reactions to install chiral centers with high enantioselectivity.
  • Fundamental research tool in organometallic chemistry and catalyst design for academic and industrial R&D laboratories.
  • Potential application in the synthesis of advanced materials and specialty chemicals requiring precise stereochemical control.

Basic Information

Product Name 1,1'-Bis((R)-(Dimethylamino)(Phenyl)Methyl)Ferrocene
CAS No. 174589-08-3
Molecular Formula C30H34FeN2
Molecular Weight 478.45 g/mol
Synonyms (R,R)-1,1'-Bis[(α-(Dimethylamino)benzyl)]ferrocene; (R,R)-1,1'-Bis(α-(N,N-Dimethylamino)benzyl)ferrocene; Josiphos-type ligand precursor; Chiral ferrocenyl diphosphine ligand precursor; (R)-1-((R)-1-(Dimethylamino)ethyl)-1'-(1-(dimethylamino)ethyl)ferrocene (common misnomer); N,N-Dimethyl-1-ferrocenylethylamine dimer; Ferrocene-based bis(amino) ligand
EINECS Contact for details

Quality Control

Our production of 1,1'-Bis((R)-(Dimethylamino)(Phenyl)Methyl)Ferrocene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high enantiomeric purity. Identity, purity, and chiral integrity are verified using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere to maximize long-term stability.

Specification

Item Specification
Appearance Orange to red-brown crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0% ee
Melting Point Contact for details
Heavy Metals < 20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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