Description

Epimedin K is a bioactive flavonoid glycoside, a key marker compound for the standardization of extracts derived from *Epimedium* species. This high-purity reference standard is essential for ensuring product quality, consistency, and efficacy in research and manufacturing. It is primarily utilized by the pharmaceutical, nutraceutical, and research sectors for analytical method development, quality control, and as a critical component in botanical drug development.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative analysis of Epimedium extracts in drug formulations.
• Nutraceutical & Dietary Supplement QC: Serves as a primary marker for the standardization and potency verification of herbal supplements containing Horny Goat Weed.
• Biomedical Research: Employed in pharmacological and pharmacokinetic studies to investigate its bioactive properties and mechanisms of action.
• Analytical Method Development: Critical for developing and validating HPLC, UPLC, and LC-MS/MS methods in quality control laboratories.
• Botanical Drug Development: Acts as a key constituent for ensuring batch-to-batch consistency and meeting regulatory requirements for botanical drug products.
• Academic Research: Used in universities and research institutes for studies related to natural product chemistry and bioactivity.

Basic Information

Product Name	Epimedin K
CAS No.	174286-13-6
Molecular Formula	C₃₉H₅₀O₁₉
Molecular Weight	826.81 g/mol
Synonyms	Epimedin K; Epimedoside K; Icariside E5; 3-O-[α-L-Rhamnopyranosyl-(1→2)-α-L-rhamnopyranosyl]-7-O-[β-D-glucopyranosyl]-5-hydroxy-4'-methoxy-8-(3-methylbut-2-enyl)flavone; 5-Hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-4H-chromen-4-one
EINECS	Contact for details

Quality Control

Our Epimedin K is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for reference materials and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.