Description

Methyl 4-(Tributylstannyl)Thiazole-2-Carboxylate is a high-value organotin intermediate featuring a functionalized thiazole core. This compound is critical for facilitating efficient Stille cross-coupling reactions, enabling the synthesis of complex heterocyclic architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing novel active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel thiazole-containing drug candidates, particularly in oncology and anti-infective research.
• Stille Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between the thiazole ring and various aryl or vinyl halides under mild conditions.
• Material Science Research: Used in the development of organic semiconductors, ligands for catalysis, and photoactive materials due to the tunable electronic properties of the thiazole moiety.
• Agrochemical Synthesis: Intermediate for creating new generations of herbicides and fungicides with heterocyclic activity centers.
• Chemical Biology Probes: Serves as a precursor for labeling reagents or molecular probes targeting biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	Methyl 4-(Tributylstannyl)Thiazole-2-Carboxylate
CAS No.	173979-00-5
Molecular Formula	C17H31NO2SSn
Molecular Weight	440.20 g/mol
Synonyms	Methyl 4-(tributylstannyl)-1,3-thiazole-2-carboxylate; 2-Thiazolecarboxylic acid, 4-(tributylstannyl)-, methyl ester; 4-Tributylstannylthiazole-2-carboxylic acid methyl ester; Tributyl(2-methoxycarbonylthiazol-4-yl)stannane; Methyl 4-tributylstannanylthiazole-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-(Tributylstannyl)Thiazole-2-Carboxylate is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and consistency for your critical research and development projects. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage under an inert atmosphere (argon or nitrogen) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Tin (Sn) Content	Contact for details
Solubility	Soluble in common organic solvents (THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.