Description

2,2-Bis(Hydroxymethyl) Malonic Acid is a versatile polyfunctional organic compound featuring both carboxylic acid and multiple hydroxyl groups. This unique structure makes it a valuable building block and intermediate for synthesizing complex molecules, including dendrimers, polymers, and pharmaceutical actives. It is particularly sought after by research institutions, fine chemical manufacturers, and pharmaceutical developers for applications requiring precise molecular architecture and functionalization.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, leveraging its multiple reactive sites for conjugation.
• Dendrimer & Polymer Synthesis: Acts as a core monomer or branching unit for creating hyperbranched polymers and dendrimers with controlled architecture for drug delivery systems.
• Crosslinking Agent: Utilized in the production of specialty resins, coatings, and adhesives where its polyfunctionality enables the formation of robust, cross-linked networks.
• Chelating Agent Precursor: Used to synthesize complexing agents for metal ions in various industrial and analytical processes.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules, including natural product analogs and novel materials.
• Surface Modification: Functionalizes surfaces of nanoparticles or other materials to introduce hydroxyl groups, enhancing hydrophilicity and further reactivity.

Basic Information

Item	Detail
Product Name	2,2-Bis(Hydroxymethyl) Malonic Acid
CAS No.	173783-71-6
Molecular Formula	C5H8O7
Molecular Weight	180.11 g/mol
Synonyms	2,2-Bis(hydroxymethyl)propanedioic Acid; Tetrahydroxysuccinic Acid; 1,1,3,3-Propanetetracarboxylic Acid; Dihydroxymalonic Acid Dimer; Bis(hydroxymethyl)malonic Acid; Malonic Acid, 2,2-bis(hydroxymethyl)-; Tetrahydroxy succinic acid
EINECS	Contact for details

Quality Control

Our 2,2-Bis(Hydroxymethyl) Malonic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for all critical parameters are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.