Description

(1S,2S)-1,2-Bis(Methanesulfonyloxymethyl)Cyclohexane is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its core value lies in its utility as a key precursor for constructing complex, stereodefined molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially those requiring specific (1S,2S) stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Asymmetric Synthesis: Used in reactions requiring the introduction of the (1S,2S) cyclohexane backbone with high enantiomeric purity for constructing stereocenters.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Polymer Chemistry: Potential monomer or cross-linking agent for creating specialty polymers with defined stereoregularity.
• Agrochemical Research: Intermediate in the development of novel, stereospecific pesticides and herbicides.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and scale-up process optimization.

Basic Information

Product Name	(1S,2S)-1,2-Bis(Methanesulfonyloxymethyl)Cyclohexane
CAS No.	173658-50-9
Molecular Formula	C₁₀H₂₀O₆S₂
Molecular Weight	324.39 g/mol
Synonyms	(1S,2S)-Cyclohexane-1,2-diylbis(methylene) dimethanesulfonate; (1S,2S)-1,2-Bis(mesyloxymethyl)cyclohexane; (1S,2S)-Bis(methanesulfonyloxymethyl)cyclohexane; (1S,2S)-1,2-Di(methanesulfonyloxymethyl)cyclohexane; (1S,2S)-Cyclohexane-1,2-dimethanol dimethanesulfonate; (1S,2S)-CHDM dimethanesulfonate; (1S-cis)-1,2-Bis[(methylsulfonyl)oxy]methyl]cyclohexane
EINECS	Contact for details

Quality Control

Our (1S,2S)-1,2-Bis(Methanesulfonyloxymethyl)Cyclohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity compliant with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.