Description

2-Thiazolylzinc Bromide is a highly reactive organozinc reagent used in modern synthetic chemistry. This compound matters as a versatile building block for the efficient formation of carbon-carbon bonds, enabling the synthesis of complex heterocyclic structures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced intermediates.

Application

This organometallic reagent is a key intermediate in various advanced synthetic transformations, including:

• Pharmaceutical Intermediates: Synthesis of thiazole-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Production of novel fungicides, herbicides, and insecticides featuring the thiazole moiety.
• Cross-Coupling Reactions: Used in Negishi, Kumada, and other transition-metal catalyzed cross-couplings to introduce the 2-thiazolyl group.
• Material Science Research: Development of organic semiconductors, ligands for catalysis, and functional polymers.
• Fine Chemical Production: Manufacture of specialty chemicals, dyes, and complex fragrance molecules.

Basic Information

Product Name	2-Thiazolylzinc Bromide
CAS No.	173382-28-0
Molecular Formula	C3H2BrNSZn
Molecular Weight	220.41 g/mol
Synonyms	2-Thiazolylzinc bromide solution; Zinc, bromo(2-thiazolyl)-; Thiazol-2-ylzinc bromide; 2-Thiazolylzinc bromide (0.5M in THF); Bromo(2-thiazolyl)zinc; 2-Thienylzinc bromide (common misnomer); 2-Thiazolyl zinc bromide; (Thiazol-2-yl)zinc bromide
EINECS	Contact for details

Quality Control

Our 2-Thiazolylzinc Bromide is produced under stringent quality protocols. Each batch undergoes rigorous analytical testing to ensure consistency, purity, and reactivity. Certificates of Analysis (COA) detailing assay, concentration, and solvent content are provided with every shipment. We adhere to cGMP principles for the production of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container must be kept sealed and handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in Tetrahydrofuran (THF)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.