Description

6-Quinolinyl Trifluoromethanesulfonate is a high-value, versatile triflate ester building block used in advanced organic synthesis. This compound is particularly valued for its role as a reactive intermediate in cross-coupling reactions, enabling the efficient construction of complex heterocyclic systems. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity reagents for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in creating advanced active ingredients for crop protection products.
• Catalytic Cross-Coupling Reactions: Serves as an excellent electrophile in palladium-catalyzed reactions such as Suzuki, Negishi, and Stille couplings to form carbon-carbon bonds.
• Materials Science Research: Employed in the development of organic electronic materials, including ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in probe development and bioconjugation strategies.
• Academic & Process R&D: A critical reagent for method development and scaling novel synthetic routes in research laboratories.

Basic Information

Product Name	6-Quinolinyl Trifluoromethanesulfonate
CAS No.	173089-80-0
Molecular Formula	C₁₀H₆F₃NO₃S
Molecular Weight	277.22 g/mol
Synonyms	6-Quinolyl Triflate; 6-Quinolinol Trifluoromethanesulfonate; 6-Hydroxyquinoline Triflate; 6-(Trifluoromethanesulfonyloxy)quinoline; Quinolin-6-yl Trifluoromethanesulfonate; 6-OTf Quinoline; 6-Quinolinyl Triflate; Trifluoromethanesulfonic Acid 6-Quinolinyl Ester
EINECS	Contact for details

Quality Control

Our 6-Quinolinyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, assay, and impurity profiles. Our quality commitment ensures the consistency and reliability required for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.