Description

1-(3-Bromoprop-1-Yn-1-Yl)-4-Methoxybenzene is a specialized aromatic alkyne building block used in advanced organic synthesis. This compound matters for its role as a key intermediate in constructing complex molecular architectures, particularly in pharmaceutical and materials science research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring alkyne functionalization.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An effective substrate in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Chemical Biology Probes: Utilized in click chemistry (e.g., CuAAC) for bioconjugation and the labeling of biomolecules.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	1-(3-Bromoprop-1-Yn-1-Yl)-4-Methoxybenzene
CAS No.	173019-85-7
Molecular Formula	C10H9BrO
Molecular Weight	225.08 g/mol
Synonyms	4-Methoxyphenyl propargyl bromide; 1-Bromo-3-(4-methoxyphenyl)propyne; 3-(4-Methoxyphenyl)-1-bromo-1-propyne; 3-Bromo-1-(4-methoxyphenyl)-1-propyne; p-Methoxyphenyl propargyl bromide; 4-Methoxybenzene, 1-(3-bromo-1-propyn-1-yl)-; (4-Methoxyphenyl)propargyl bromide
EINECS	Contact for details

Quality Control

Our 1-(3-Bromoprop-1-Yn-1-Yl)-4-Methoxybenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the light-sensitive nature of the compound, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.