Description

(R)-2-{o-{(n-Benzylprolyl)Amino}Phenyl}-Benzylideneamino-Acetato(2-)-N,N',N''-Nickel(II) is a sophisticated organometallic complex featuring a chiral, tetradentate ligand system. This compound is valued for its role as a highly selective catalyst or chiral auxiliary in advanced organic synthesis, particularly in asymmetric transformations. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers developing enantiomerically pure active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Asymmetric Catalysis: Employed as a chiral catalyst for enantioselective C-H activation, cyclopropanation, or other carbon-heteroatom bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Key reagent in the synthesis of complex, chiral molecules for drug discovery and development programs.
• Ligand Precursor: Serves as a starting material or model complex for developing novel chiral ligand libraries for transition metal catalysis.
• Academic & Industrial Research: Used in methodological studies to explore new catalytic pathways and reaction mechanisms in organometallic chemistry.
• Fine Chemical Production: Applied in the pilot-scale or small-batch manufacturing of high-value, optically pure specialty chemicals.

Basic Information

Product Name	(R)-2-{o-{(n-Benzylprolyl)Amino}Phenyl}-Benzylideneamino-Acetato(2-)-N,N',N''-Nickel(II)
CAS No.	172924-51-5
Molecular Formula	C33H30N4NiO2
Molecular Weight	573.32 g/mol
Synonyms	(R)-2-{o-[(N-Benzylprolyl)Amino]Phenyl}-Benzylideneamino-Acetato(2-)-N,N',N''-Nickel(II); Nickel, [N-[(2-[[(2-benzyl-1-oxo-1-pyrrolidinyl)amino]phenyl]methylene]glycinato(2-)-.kappa.N1,.kappa.O]-, (SP-4-2)-; (R)-NBPBA-Ni(II) Complex; (R)-N-Benzylprolyl-Benzylideneamino-Acetato Nickel(II); Chiral Nickel(II) Schiff Base Complex; Nickel(II) complex with N-benzylproline-derived tetradentate ligand; Asymmetric Nickel Catalyst 172924-51-5
EINECS	Contact for details

Quality Control

Every batch of our (R)-2-{o-{(n-Benzylprolyl)Amino}Phenyl}-Benzylideneamino-Acetato(2-)-N,N',N''-Nickel(II) is synthesized and purified under controlled conditions to ensure high chiral purity and catalytic performance. Our products undergo rigorous quality testing, including chiral HPLC and elemental analysis, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and spectroscopic data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, cool place. This compound is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or light will degrade its catalytic activity.

Specification

Item	Specification
Appearance	Green to dark green crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 98.0%
Nickel Content	9.8 - 10.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.