Description

4-n-Boc-Amino-4-Carboxytetrahydropyran is a high-purity, protected amino acid derivative widely used as a critical building block in organic synthesis. This compound is essential for the efficient construction of complex molecules, offering a versatile handle for peptide coupling and further functionalization. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers in the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetics & Peptide Chemistry: Serves as a protected amino acid building block for solid-phase and solution-phase peptide synthesis.
• Protease Inhibitor Development: Used in the research and production of inhibitors targeting various proteolytic enzymes.
• Combinatorial Chemistry Libraries: Employed to generate diverse compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Facilitates the creation of labeled or modified biomolecules for studying biological pathways.
• Academic & Industrial Research: A valuable reagent for methodological development and synthetic chemistry research.

Basic Information

Product Name	4-n-Boc-Amino-4-Carboxytetrahydropyran
CAS No.	172843-97-9
Molecular Formula	C11H19NO5
Molecular Weight	245.27 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]tetrahydro-2H-pyran-4-carboxylic Acid; 4-(Boc-amino)tetrahydropyran-4-carboxylic Acid; 4-(tert-Butoxycarbonylamino)tetrahydropyran-4-carboxylic Acid; 4-Boc-Amino-THP-4-Carboxylic Acid; 4-N-Boc-4-Carboxytetrahydropyran; Boc-4-Amino-THP-4-COOH; 172843-97-9; tert-Butyl 4-carboxy-4-(aminomethyl)tetrahydropyran-1-carboxylate (related structure)
EINECS	Contact for details

Quality Control

Our 4-n-Boc-Amino-4-Carboxytetrahydropyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.