Description

.Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-2-(2-Cyanoethyl)-2,3-Dideoxy-4-o-(Phenylmethyl)- is a sophisticated carbohydrate derivative and a key protected intermediate in organic synthesis. This compound matters for its role as a versatile chiral building block, enabling the precise construction of complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other bioactive molecules where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Antiviral Drug Research: Used in the research and development of prodrugs and modified nucleosides targeting viral polymerases.
• Carbohydrate Chemistry: Serves as a protected glycosyl donor or acceptor for the construction of complex oligosaccharides and glycoconjugates.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic applications.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: A valuable tool for chemists studying stereoselective synthesis, glycosylation reactions, and the chemical biology of carbohydrates.

Basic Information

Product Name	.Beta.-D-Ribo-Hexopyranose, 1,6-Anhydro-2-(2-Cyanoethyl)-2,3-Dideoxy-4-o-(Phenylmethyl)-
CAS No.	172227-40-6
Molecular Formula	C16H19NO4
Molecular Weight	289.33 g/mol
Synonyms	1,6-Anhydro-2-(2-cyanoethyl)-2,3-dideoxy-4-O-benzyl-β-D-ribo-hexopyranose; 4-O-Benzyl-1,6-anhydro-2-(2-cyanoethyl)-2,3-dideoxy-β-D-ribo-hexopyranose; 1,6-Anhydro-4-O-benzyl-2,3-dideoxy-2-(2-cyanoethyl)-β-D-ribo-hexopyranose; Benzyl 1,6-anhydro-2,3-dideoxy-2-(2-cyanoethyl)-β-D-ribo-hexopyranoside (ambiguous); Protected D-ribose derivative; Anhydro ribose benzyl ether cyanoethyl derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay and impurity profiles are available upon request. We adhere to a cGMP-compliant quality management system for production relevant to pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.