Description

5,6-Dihydro-2H-Thiopyran-3-Carboxylic Acid is a versatile sulfur-containing heterocyclic building block with a carboxylic acid functional group. This compound is valued for its unique structural motif, which is integral to the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel therapeutic agents, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiopyran ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or photonic properties.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	5,6-Dihydro-2H-Thiopyran-3-Carboxylic Acid
CAS No.	172214-44-7
Molecular Formula	C6H8O2S
Molecular Weight	144.19 g/mol
Synonyms	3-Thiopyran-3-carboxylic acid, 5,6-dihydro-2H-; 5,6-Dihydro-2H-thiopyran-3-carboxylic acid; 3-Carboxy-5,6-dihydro-2H-thiopyran; Dihydro-2H-thiopyran-3-carboxylic acid; Tetrahydrothiopyran-3-carboxylic acid (related saturated form); 3-Thiopyrancarboxylic acid, 5,6-dihydro-
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-2H-Thiopyran-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.