Description

1-Fluoro-4-Hydroxy-1,4-Diazoniabicyclo[2.2.2]Octane Bis(Tetrafluoroborate) is a highly reactive and versatile fluorinating and oxidizing agent, belonging to the class of electrophilic N-F reagents. This compound matters for its ability to introduce fluorine atoms or facilitate oxidation reactions under mild conditions, offering chemists a powerful tool for synthesizing complex molecules. It is primarily needed by R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel fluorinated compounds and fine chemical intermediates.

Application

• Electrophilic Fluorination: A key reagent for the selective introduction of fluorine into organic molecules, crucial for developing pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability.
• Oxidation Reactions: Used as a potent oxidant in organic synthesis to convert alcohols to carbonyl compounds or to generate other reactive intermediates.
• Pharmaceutical Intermediate Synthesis: Enables the synthesis of fluorinated active pharmaceutical ingredients (APIs) and complex drug candidates in medicinal chemistry research.
• Agrochemical Research: Applied in the development of novel fluorinated pesticides and herbicides, where the fluorine atom can significantly alter biological activity and environmental persistence.
• Material Science: Used in the surface modification of polymers and the synthesis of fluorinated monomers for specialty polymers with unique properties.
• Radiochemistry: Potential utility in the synthesis of precursors for Positron Emission Tomography (PET) imaging agents containing fluorine-18.

Basic Information

Item	Details
Product Name	1-Fluoro-4-Hydroxy-1,4-Diazoniabicyclo[2.2.2]Octane Bis(Tetrafluoroborate)
CAS No.	172090-26-5
Molecular Formula	C6H12F9N2O1B2
Molecular Weight	329.78 g/mol
Synonyms	1-Fluoro-4-hydroxy-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate); Accufluor™ NFTh (Trade Name); N-Fluoropyridinium tetrafluoroborate analogue; Electrophilic N-F reagent; 1-Fluoro-4-hydroxy-DABCO bis(BF4); Fluorinating reagent 172090-26-5; 4-Fluoro-1-hydroxy-1,4-diazoniabicyclo[2.2.2]octane ditetrafluoroborate
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-Hydroxy-1,4-Diazoniabicyclo[2.2.2]Octane Bis(Tetrafluoroborate) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity, consistency, and performance for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., argon or nitrogen) in its original sealed packaging to prevent decomposition. Keep away from incompatible materials such as strong reducing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Solubility	Soluble in polar aprotic solvents (e.g., acetonitrile, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.