Description

3-Thienylzinc Iodide is a versatile organozinc reagent, a key building block for the formation of carbon-carbon bonds in complex organic synthesis. Its value lies in its high reactivity and selectivity, particularly in cross-coupling reactions, enabling the efficient construction of thiophene-containing molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic intermediates for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of active pharmaceutical ingredients (APIs) containing thiophene or bithiophene scaffolds, which are prevalent in various therapeutic areas.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides where the thiophene moiety imparts specific biological activity.
• Material Science & OLED Development: Serves as a precursor for constructing conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and semiconductors.
• Negishi Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Negishi couplings with aryl or vinyl halides to form biaryl or styryl compounds.
• Ligand and Catalyst Preparation: Useful for the functionalization of complex ligands and the preparation of organometallic catalysts for asymmetric synthesis.
• Fine Chemical and Specialty Chemical Production: Enables the tailored synthesis of complex, high-value specialty chemicals for research and industrial applications.

Basic Information

Product Name	3-Thienylzinc Iodide
CAS No.	172035-85-7
Molecular Formula	C4H3SZnI
Molecular Weight	283.41 g/mol
Synonyms	Zinc, iodothienyl-; 3-Thienylzinc iodide solution; Thiophen-3-ylzinc iodide; Iodozinc thiophen-3-ide; 3-Thienylzinc iodide 0.5M in THF; (3-Thienyl)zinc iodide; Zinc, (3-thienyl)iodo-; 3-Thienyl zinc iodide
EINECS	Contact for details

Quality Control

Our 3-Thienylzinc Iodide is produced under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as concentration, purity, and solvent content. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the exacting standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated place. Keep away from heat, sparks, and open flame. Due to its highly volatile and pyrophoric nature in certain concentrations, handle only in a certified fume hood using appropriate techniques for air-sensitive reagents.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in THF (Typical)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms
Solvent Content (GC)	Balance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.