Description

2-Butylzinc Bromide is a highly reactive organozinc reagent, specifically an alkylzinc halide, with the CAS number 171860-66-5. It serves as a critical building block in organic synthesis, enabling efficient carbon-carbon bond formation through reactions like Negishi cross-coupling. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require precise and selective alkylation steps.

Application

• Negishi Cross-Coupling Reactions: A premier reagent for the palladium-catalyzed coupling with aryl, heteroaryl, or vinyl halides to form new C-C bonds.
• Pharmaceutical Intermediate Synthesis: Used in the construction of complex drug molecules, particularly for introducing butyl groups with high selectivity.
• Agrochemical Active Ingredient Development: Employed in the synthesis of herbicides, fungicides, and insecticides requiring specific alkyl chain modifications.
• Advanced Material Precursors: Facilitates the synthesis of organic ligands and monomers for polymers, liquid crystals, and OLED materials.
• Fine Chemical and Specialty Chemical Production: Key for manufacturing flavors, fragrances, and other high-value chemicals where traditional Grignard reagents may be less suitable.
• Academic and Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-Butylzinc Bromide
CAS No.	171860-66-5
Molecular Formula	C4H9BrZn
Molecular Weight	202.40 g/mol
Synonyms	sec-Butylzinc Bromide; Zinc, bromo(1-methylpropyl)-; Bromo(sec-butyl)zinc; (1-Methylpropyl)zinc bromide; Bromo(2-butyl)zinc; sec-C4H9ZnBr; Butylzinc bromide (sec-); Organozinc reagent C4H9ZnBr
EINECS	Contact for details

Quality Control

Our 2-Butylzinc Bromide is manufactured under stringent quality control protocols, typically supplied as a solution in tetrahydrofuran or diethyl ether. Each batch is characterized by NMR (1H, 13C) and titration to ensure high chemical purity and accurate concentration. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee consistency and reliability for your critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized (store under inert atmosphere) and highly volatile. It must be stored under a dry, inert gas (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. Keep away from heat, sparks, open flames, and strong oxidizing agents. Use only in a well-ventilated fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (Typical)	0.5 M to 1.0 M in THF or Diethyl Ether
Assay (Titration)	≥ 95%
Identification (NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.