Description

2(3H)-Furanone, 3-Acetyldihydro-4,5-Dimethyl-, (3R,4S,5R)- (9Ci) is a high-purity, stereochemically defined lactone derivative, valued for its role as a versatile chiral building block and flavor/fragrance intermediate. Its defined stereochemistry at the 3, 4, and 5 positions makes it a critical precursor for synthesizing complex molecules with specific biological activity or sensory profiles. This compound is essential for R&D and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Synthesis: Used in the research and manufacture of advanced pesticides and herbicides that require specific stereoisomers for optimal efficacy.
• Flavor & Fragrance Ingredient: Serves as a precursor for creating lactone-based flavor compounds (e.g., creamy, coconut, buttery notes) and fragrance molecules.
• Fine Chemical Building Block: Employed in organic synthesis for constructing complex natural product analogs and specialty polymers.
• Research & Development: A valuable reference standard and starting material in academic and industrial chemistry research focused on lactone chemistry and asymmetric synthesis.

Basic Information

Product Name	2(3H)-Furanone, 3-Acetyldihydro-4,5-Dimethyl-, (3R,4S,5R)- (9Ci)
CAS No.	171039-05-7
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(3R,4S,5R)-3-Acetyldihydro-4,5-dimethylfuran-2(3H)-one; 3-Acetyl-4,5-dimethyldihydro-2(3H)-furanone; 4,5-Dimethyl-3-acetyldihydro-2(3H)-furanone; (3R,4S,5R)-4,5-Dimethyl-3-acetyldihydrofuran-2(3H)-one; Dihydro-4,5-dimethyl-3-acetyl-2(3H)-furanone; Stereoisomer of 171039-05-7; Chiral lactone intermediate; Acetyl dimethyl dihydrofuranone.
EINECS	Contact for details

Quality Control

Our production of 2(3H)-Furanone, 3-Acetyldihydro-4,5-Dimethyl-, (3R,4S,5R)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS to confirm identity, stereochemical purity, and chemical assay. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (3R,4S,5R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.