Description

(1-Methyl-1H-Pyrazol-5-Yl)Tributylstannane is a specialized organotin compound that serves as a versatile building block in advanced organic synthesis. Its core value lies in enabling efficient Stille cross-coupling reactions, a critical methodology for forming carbon-carbon bonds in complex molecule construction. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-yielding coupling partners for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in Stille cross-coupling reactions for constructing complex heterocyclic scaffolds found in drug candidates.
• Agrochemical Development: Used in the synthesis of novel pesticides and herbicides, facilitating the introduction of the pyrazole moiety.
• Materials Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Ligand Precursor: Acts as a starting material for the synthesis of specialized ligands used in catalysis.
• Complex Natural Product Synthesis: Utilized in academic and industrial research for the total synthesis of natural products with biological activity.
• Polymer Functionalization: Enables the incorporation of functional pyrazole groups into polymer backbones for specialized material properties.

Basic Information

Product Name	(1-Methyl-1H-Pyrazol-5-Yl)Tributylstannane
CAS No.	170682-50-5
Molecular Formula	C16H32N2Sn
Molecular Weight	371.14 g/mol
Synonyms	5-(Tributylstannyl)-1-methyl-1H-pyrazole; Tributyl(1-methyl-1H-pyrazol-5-yl)stannane; 1-Methyl-5-(tributylstannyl)pyrazole; (1-Methyl-1H-pyrazol-5-yl)tributyltin; Stannane, tributyl(1-methyl-1H-pyrazol-5-yl)-; Tributyl(1-methylpyrazol-5-yl)stannane
EINECS	Contact for details

Quality Control

Our (1-Methyl-1H-Pyrazol-5-Yl)Tributylstannane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. Each lot undergoes comprehensive analysis, including NMR (1H, 13C, 119Sn) for structural confirmation and HPLC or GC assay for purity determination. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C. Due to its moisture-sensitive and easily oxidized nature, the container should only be opened in a dry, inert glovebox or under a positive pressure of inert gas. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Tin (Sn) Content	Contact for details
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.