Description

6-Oxabicyclo[3.1.0]Hexane-2-Carboxylicacid,Methylester,(1Alpha,2Beta,5Alpha)-(9Ci) is a high-purity, synthetically valuable bicyclic oxirane ester. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, prized for its rigid, fused-ring structure that imparts specific stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors developing novel active ingredients, particularly in areas like antiviral and central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug molecules, including potential protease inhibitors and neuromodulators.
• Asymmetric Synthesis: Utilized as a scaffold in stereoselective reactions to construct molecules with defined three-dimensional architecture.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies due to its constrained conformation.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring specific stereocenters.
• Academic & R&D: Used in methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Item	Detail
Product Name	6-Oxabicyclo[3.1.0]Hexane-2-Carboxylicacid,Methylester,(1Alpha,2Beta,5Alpha)-(9Ci)
CAS No.	170423-00-4
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(1α,2β,5α)-6-Oxabicyclo[3.1.0]hexane-2-carboxylic acid methyl ester; Methyl (1α,2β,5α)-6-oxabicyclo[3.1.0]hexane-2-carboxylate; 6-Oxabicyclo[3.1.0]hexane-2-carboxylic acid, methyl ester, (1α,2β,5α)-; Bicyclic oxirane ester; Chiral oxabicyclohexane carboxylate
EINECS	Contact for details

Quality Control

Every batch of our 6-Oxabicyclo[3.1.0]Hexane-2-Carboxylicacid,Methylester,(1Alpha,2Beta,5Alpha)-(9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles via validated methods like HPLC, GC, and NMR. Our commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.