Description

1,4-Dioxaspiro[4.5]Dec-7-En-8-Yl Trifluoromethanesulfonate is a high-value triflate ester building block used extensively in advanced organic synthesis. Its core value proposition lies in its exceptional reactivity as a versatile electrophile, enabling efficient carbon-carbon and carbon-heteroatom bond formation under mild conditions. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key electrophile in the synthesis of complex spirocyclic and bridged-ring systems found in novel drug candidates.
• Cross-Coupling Reactions: Serves as a superior substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to introduce functionalized spirocyclic fragments.
• Nucleophilic Substitution: Enables efficient SN2-type reactions with a wide range of carbon, oxygen, nitrogen, and sulfur nucleophiles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with spirocyclic motifs.
• Material Science Precursor: Acts as a monomer or building block for creating specialized polymers and advanced organic materials.
• Asymmetric Synthesis: Employed in catalytic asymmetric transformations to generate enantiomerically enriched spirocyclic compounds.

Basic Information

Item	Details
Product Name	1,4-Dioxaspiro[4.5]Dec-7-En-8-Yl Trifluoromethanesulfonate
CAS No.	170011-47-9
Molecular Formula	C11H13F3O5S
Molecular Weight	314.28 g/mol
Synonyms	7,8-Dihydrospiro[1,3]dioxolane-2,6'-bicyclo[3.2.1]oct-6'-en-8'-yl trifluoromethanesulfonate; 1,4-Dioxaspiro[4.5]dec-7-en-8-yl triflate; 8-Trifluoromethanesulfonyloxy-1,4-dioxaspiro[4.5]dec-7-ene; Spiroketal Triflate; Bicyclo[3.2.1]oct-6-ene-8-triflate, 7,8-dihydro-1,3-benzodioxole-protected
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.5]Dec-7-En-8-Yl Trifluoromethanesulfonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and lot-to-lot consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.