Description

4-tert-Amylbenzenesulfonyl Chloride is a specialized organic sulfonyl chloride derivative, serving as a critical building block in advanced chemical synthesis. Its primary value lies in its high reactivity as a sulfonylation agent, enabling the introduction of the bulky tert-amylphenylsulfonyl group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where specific steric and electronic properties are required.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the tert-amyl group can enhance lipophilicity and biological activity.
• Polymer Chemistry: Acts as a modifying agent or chain transfer agent in the synthesis of specialty polymers with tailored properties.
• Dye and Pigment Manufacturing: Intermediate for creating sulfonated dyes and colorants with improved solubility and fastness.
• Chemical Research & Development: A versatile tool for organic chemists in academia and R&D labs for constructing complex molecular architectures.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands used in asymmetric catalysis and metal complex formation.

Basic Information

Item	Details
Product Name	4-tert-Amylbenzenesulfonyl Chloride
CAS No.	169677-20-7
Molecular Formula	C11H15ClO2S
Molecular Weight	246.75 g/mol
Synonyms	p-tert-Amylbenzenesulfonyl Chloride; 1-(1,1-Dimethylpropyl)-4-(chlorosulfonyl)benzene; 4-(1,1-Dimethylpropyl)benzenesulfonyl Chloride; 4-(tert-Pentyl)benzenesulfonyl Chloride; 4-(2-Methylbutan-2-yl)benzenesulfonyl Chloride; p-(1,1-Dimethylpropyl)benzenesulfonyl Chloride; (4-tert-Pentylphenyl)sulfonyl Chloride
EINECS	Contact for details

Quality Control

Every batch of 4-tert-Amylbenzenesulfonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and high purity suitable for synthetic applications. Our standard grade typically meets a purity specification of ≥97% (by HPLC), but custom purities are available. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.