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Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-α,-L-Fucopyranoside CAS NO 169532-17-6
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CAS No.:169532-17-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-α,-L-Fucopyranoside is a sophisticated, synthetically derived thioglycoside building block, specifically protected for advanced organic synthesis. This compound is of critical importance for the stereoselective construction of complex carbohydrate mimetics and glycoconjugates, offering precise control over glycosidic linkage formation. It is an essential intermediate for researchers and manufacturers in pharmaceutical development, glycobiology research, and the synthesis of novel diagnostic agents.
Application
- Key Intermediate in Oligosaccharide Synthesis: Used for the stereocontrolled assembly of L-fucose-containing oligosaccharides and glycans.
- Pharmaceutical Research: Serves as a crucial building block for developing glycomimetic drugs, enzyme inhibitors, and carbohydrate-based vaccines.
- Glycoconjugate Production: Employed in the synthesis of neoglycoproteins, glycolipids, and other biologically active conjugates for biochemical studies.
- Chemical Biology Probes: Utilized to create labeled or tagged carbohydrate probes for investigating protein-carbohydrate interactions and cell surface recognition events.
- Process Development: Acts as a standard or starting material for scaling up the production of fucose-related active pharmaceutical ingredients (APIs).
Basic Information
| Item | Details |
|---|---|
| Product Name | Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-α,-L-Fucopyranoside |
| CAS No. | 169532-17-6 |
| Molecular Formula | C29H34O4S |
| Molecular Weight | 478.64 g/mol |
| Synonyms | Ethyl 2,3,4-Tri-O-benzyl-1-thio-α-L-fucopyranoside; 1-Thioethyl 2,3,4-tri-O-benzyl-α-L-fucopyranoside; α-L-Fucopyranoside, ethyl 2,3,4-tri-O-benzyl-1-thio-; Ethyl 1-thio-2,3,4-tri-O-benzyl-α-L-fucopyranoside; 1-S-Ethyl-2,3,4-tri-O-benzyl-1-thio-α-L-fucopyranose; Protected L-Fucose thioglycoside donor |
| EINECS | Contact for details |
Quality Control
Our Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-α,-L-Fucopyranoside is produced under strict quality management to ensure batch-to-batch consistency and high purity suitable for research and process applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and optical rotation for stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Specific Optical Rotation | Contact for details |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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