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Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-α,-L-Fucopyranoside CAS NO 169532-17-6


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CAS No.:169532-17-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-α,-L-Fucopyranoside is a sophisticated, synthetically derived thioglycoside building block, specifically protected for advanced organic synthesis. This compound is of critical importance for the stereoselective construction of complex carbohydrate mimetics and glycoconjugates, offering precise control over glycosidic linkage formation. It is an essential intermediate for researchers and manufacturers in pharmaceutical development, glycobiology research, and the synthesis of novel diagnostic agents.

Application

  • Key Intermediate in Oligosaccharide Synthesis: Used for the stereocontrolled assembly of L-fucose-containing oligosaccharides and glycans.
  • Pharmaceutical Research: Serves as a crucial building block for developing glycomimetic drugs, enzyme inhibitors, and carbohydrate-based vaccines.
  • Glycoconjugate Production: Employed in the synthesis of neoglycoproteins, glycolipids, and other biologically active conjugates for biochemical studies.
  • Chemical Biology Probes: Utilized to create labeled or tagged carbohydrate probes for investigating protein-carbohydrate interactions and cell surface recognition events.
  • Process Development: Acts as a standard or starting material for scaling up the production of fucose-related active pharmaceutical ingredients (APIs).

Basic Information

Item Details
Product Name Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-α,-L-Fucopyranoside
CAS No. 169532-17-6
Molecular Formula C29H34O4S
Molecular Weight 478.64 g/mol
Synonyms Ethyl 2,3,4-Tri-O-benzyl-1-thio-α-L-fucopyranoside; 1-Thioethyl 2,3,4-tri-O-benzyl-α-L-fucopyranoside; α-L-Fucopyranoside, ethyl 2,3,4-tri-O-benzyl-1-thio-; Ethyl 1-thio-2,3,4-tri-O-benzyl-α-L-fucopyranoside; 1-S-Ethyl-2,3,4-tri-O-benzyl-1-thio-α-L-fucopyranose; Protected L-Fucose thioglycoside donor
EINECS Contact for details

Quality Control

Our Ethyl 2,3,4-Tri-o-Benzyl-1-Thio-α,-L-Fucopyranoside is produced under strict quality management to ensure batch-to-batch consistency and high purity suitable for research and process applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and optical rotation for stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Specific Optical Rotation Contact for details
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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