Description

6-Amino-3-Phenyl-4-(Thiophen-2-Yl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-value, multi-functional heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its complex fused-ring structure, featuring pyrazole, pyran, and thiophene moieties, makes it a versatile scaffold for constructing novel molecules with targeted biological or material properties. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in libraries targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a starting material for creating specialized organic ligands, dyes, or photoactive compounds for advanced materials.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or protein-ligand interactions due to its diverse functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring complex heterocyclic frameworks.

Basic Information

Product Name	6-Amino-3-Phenyl-4-(Thiophen-2-Yl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	168429-61-6
Molecular Formula	C17H12N4OS
Molecular Weight	320.37 g/mol
Synonyms	6-Amino-3-phenyl-4-(thiophen-2-yl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-3-phenyl-4-(2-thienyl)-; 4-(Thiophen-2-yl)-6-amino-3-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; Pyrano[2,3-c]pyrazole derivative CN-168429-61-6; 6-Amino-4-(2-thienyl)-3-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Phenyl-4-(Thiophen-2-Yl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure consistent high quality and batch-to-batch reproducibility. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.