Description

Lixivaptan is a potent, selective, and orally active non-peptide vasopressin V2 receptor antagonist. This compound is of significant interest in pharmaceutical research and development for its potential therapeutic applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel treatments for conditions related to fluid retention.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting vasopressin receptors.
• Research Chemical: Used in preclinical and clinical research to study the role of vasopressin in physiology and disease.
• Drug Discovery & Development: Serves as a reference standard and lead compound for developing new therapies for hyponatremia (low blood sodium).
• Biochemical Research: Employed in receptor binding assays and pharmacological studies to understand V2 receptor antagonism.
• Formulation Studies: Used in the development of dosage forms, such as tablets or capsules, for clinical trials.
• Metabolism and Pharmacokinetics (DMPK) Studies: Investigated to understand the absorption, distribution, metabolism, and excretion profile of vasopressin antagonists.

Basic Information

Product Name	Lixivaptan
CAS No.	168079-32-1
Molecular Formula	C₂₇H₂₆ClN₃O₂
Molecular Weight	459.97 g/mol
Synonyms	VPA-985; WAY-VPA-985; 5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl]benzamide; (R)-VPA-985; Lixivaptanum; UNII-2S2P2O9Q5G
EINECS	Contact for details

Quality Control

Our Lixivaptan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.