Description

2-Amino-2-(4-(Trifluoromethyl)Phenyl)Acetonitrile is a high-value, versatile chemical intermediate characterized by its unique trifluoromethylphenyl and nitrile functionalities. This compound matters for its critical role in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging the biological activity imparted by the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, crucial for producing enantiomerically pure compounds.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and polar functional groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Amino-2-(4-(Trifluoromethyl)Phenyl)Acetonitrile
CAS No.	167024-67-1
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	α-Amino-4-(trifluoromethyl)benzeneacetonitrile; (4-Trifluoromethylphenyl)glycinonitrile; 2-Amino-2-[4-(trifluoromethyl)phenyl]acetonitrile; 4-(Trifluoromethyl)phenylglycinonitrile; 2-Amino-2-(4-trifluoromethylphenyl)acetonitrile; 2-Amino-2-(alpha,alpha,α-trifluoro-p-tolyl)acetonitrile; Benzeneacetonitrile, α-amino-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(4-(Trifluoromethyl)Phenyl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for your synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.