Description

5-Chloro-3-Methylbenzo[B]Thiophene-2-Sulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative essential for advanced organic synthesis. This compound serves as a critical building block for creating complex molecules, offering a reactive handle for the introduction of sulfonamide or sulfonate groups. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with sulfonamide-based activity.
• Material Science Research: Building block for creating specialized polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design of activity-based probes for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	5-Chloro-3-Methylbenzo[B]Thiophene-2-Sulfonyl Chloride
CAS No.	166964-33-6
Molecular Formula	C9H6Cl2O2S2
Molecular Weight	281.17 g/mol
Synonyms	5-Chloro-3-methyl-2-benzothiophenesulfonyl chloride; 5-Chloro-3-methylbenzo[b]thiophene-2-sulfonyl chloride; 2-Benzothiophenesulfonyl chloride, 5-chloro-3-methyl-; 3-Methyl-5-chlorobenzo[b]thiophene-2-sulfonyl chloride; 5-Chloro-3-methylbenzo[b]thiophene-2-sulphonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-3-Methylbenzo[B]Thiophene-2-Sulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality management and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.