Description

1-(6,7-Dichloro-8-Nitro-2,3-Dihydro-1,4-Benzodioxin-5-Yl)-1-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzodioxin core structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting complex biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those exploring benzodioxin-based pharmacophores for central nervous system (CNS) or anti-inflammatory applications.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides or pesticides, leveraging its nitro and chloro substituents for biological activity.
• Material Science: Potential use in the synthesis of specialty polymers or organic electronic materials due to its fused heterocyclic structure.
• Chemical Synthesis Reference Standard: Used as a pure standard in analytical chemistry for method development and quality control in complex organic synthesis.
• Academic & Institutional Research: Employed in universities and research institutes for studying heterocyclic chemistry, nitration reactions, and structure-activity relationships (SAR).

Basic Information

Product Name	1-(6,7-Dichloro-8-Nitro-2,3-Dihydro-1,4-Benzodioxin-5-Yl)-1-Ethanone
CAS No.	166816-12-2
Molecular Formula	C10H7Cl2NO5
Molecular Weight	292.07 g/mol
Synonyms	5-Acetyl-6,7-dichloro-8-nitro-2,3-dihydro-1,4-benzodioxine; 6,7-Dichloro-8-nitro-2,3-dihydro-1,4-benzodioxin-5-yl ethanone; 1-(6,7-Dichloro-8-nitro-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)ethanone; 5-Acetyl-6,7-dichloro-8-nitro-1,4-benzodioxane; CAS 166816-12-2
EINECS	Contact for details

Quality Control

Our 1-(6,7-Dichloro-8-Nitro-2,3-Dihydro-1,4-Benzodioxin-5-Yl)-1-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.