Description

4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Vinyl]-Benzoic Acid is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its unique sterically hindered polycyclic structure, which serves as a key building block for creating complex molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting nuclear receptors.
• Organic Synthesis Building Block: Used to construct complex polycyclic frameworks and sterically hindered compounds in research and development.
• Material Science Research: Serves as a monomer or precursor for developing advanced organic materials with specific optical or electronic properties.
• Agrochemical Synthesis: Potential intermediate in the development of new generation pesticides and plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Vinyl]-Benzoic Acid
CAS No.	166175-31-1
Molecular Formula	C24H28O2
Molecular Weight	348.48 g/mol
Synonyms	2-[2-(4-Carboxyphenyl)ethenyl]-3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene; 4-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)vinyl]benzoic Acid; Bexarotene Impurity; LG-100754; LG100754; Targretin Impurity; Tetramethyltetralin Derivative
EINECS	Contact for details

Quality Control

Our production of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Vinyl]-Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.