Description

3-(Tributylstannyl)Isoquinoline is a specialized organotin compound where a tributyltin group is attached to the isoquinoline heterocycle, serving as a versatile building block in advanced organic synthesis. This compound is valued for its role in facilitating key carbon-carbon and carbon-heteroatom bond-forming reactions, particularly in the synthesis of complex pharmaceutical intermediates and functional materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate the isoquinoline scaffold into target molecules via efficient metal-mediated coupling strategies.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the Stille cross-coupling reaction to construct complex isoquinoline-containing drug candidates, such as kinase inhibitors or alkaloid analogs.
• Agrochemical Research: Used in the development of novel active ingredients by enabling the introduction of the isoquinoline moiety into lead structures.
• Material Science & OLED Development: Acts as a precursor for creating organic semiconductors, light-emitting materials, and charge-transport layers where the isoquinoline unit is required.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized organometallic catalysts and ligands for asymmetric catalysis.
• Academic & R&D Laboratories: Serves as a fundamental research chemical for methodological development in organometallic chemistry and new synthetic pathway exploration.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	3-(Tributylstannyl)Isoquinoline
CAS No.	166114-73-4
Molecular Formula	C21H33NSn
Molecular Weight	426.20 g/mol
Synonyms	3-(Tributylstannyl)isoquinoline; Tributyl(isoquinolin-3-yl)stannane; Stannane, tributyl(3-isoquinolinyl)-; 3-Tributylstannylisoquinoline; Isoquinoline, 3-(tributylstannyl)-; 3-(Tri-n-butylstannyl)isoquinoline; 3-SnBu3-Isoquinoline
EINECS	Contact for details

Quality Control

Our 3-(Tributylstannyl)Isoquinoline is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and can support regulatory documentation needs for advanced R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is between 2°C and 8°C. Keep away from strong bases and incompatible materials. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	27.0 - 28.5 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.