Description

2-Pyridinylmethyl Zinc Chloride is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, particularly in cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of novel drug candidates, especially those containing pyridine or substituted pyridine motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides requiring specific heterocyclic structures.
• Cross-Coupling Reactions: Serves as a nucleophilic coupling partner in Negishi and related cross-coupling reactions to form biaryl and other C-C bonds.
• Ligand Precursor: Acts as a starting material for the preparation of specialized N-donor ligands used in catalysis.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Fine Chemical Production: Utilized for the custom synthesis of complex, high-value organic molecules for various industrial applications.

Basic Information

Product Name	2-Pyridinylmethyl Zinc Chloride
CAS No.	165334-81-6
Molecular Formula	C6H6ClNZn
Molecular Weight	192.95 g/mol
Synonyms	(2-Pyridylmethyl)zinc chloride; Zinc, chloro(2-pyridinylmethyl)-; (Pyridin-2-ylmethyl)zinc chloride; 2-Pyridylmethylzinc chloride; 2-Picolylzinc chloride; Chloro(2-pyridinylmethyl)zinc; (2-Picolyl)zinc chloride
EINECS	Contact for details

Quality Control

Our 2-Pyridinylmethyl Zinc Chloride is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, assay, and impurity profiles. Our quality system is designed to meet the exacting standards required for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for extended stability. Keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to beige powder or solution
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 95% (as Zn complex)
Solvent (if supplied as solution)	Specified (e.g., THF, DMF)
Concentration (if solution)	0.5 M, 1.0 M, or as requested

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.