Description

4-(4-Bromophenyl)-Tetrahydro-2H-Pyran-4-Ol is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a substituted phenyl ring with a functionalized tetrahydropyran, making it a critical intermediate for constructing complex pharmacophores. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it serves as a key precursor for structure-activity relationship (SAR) studies and lead optimization.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including novel coupling and cyclization reactions.

Basic Information

Product Name	4-(4-Bromophenyl)-Tetrahydro-2H-Pyran-4-Ol
CAS No.	165119-46-0
Molecular Formula	C11H13BrO2
Molecular Weight	257.12 g/mol
Synonyms	4-(4-Bromophenyl)tetrahydro-2H-pyran-4-ol; 4-(p-Bromophenyl)-4-hydroxytetrahydropyran; 4-Hydroxy-4-(4-bromophenyl)tetrahydropyran; 4-(4-Bromophenyl)-4-hydroxytetrahydropyran; 4-(4-Bromophenyl)-4-hydroxyoxane; THP-protected 4-bromobenzyl alcohol derivative; 4-Bromophenyl tetrahydropyran-4-yl alcohol
EINECS	Contact for details

Quality Control

Our 4-(4-Bromophenyl)-Tetrahydro-2H-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent batch-to-batch performance. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing identity, purity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.