Description

(17β)-n-[2,5-Bis(Trifluoromethyl)Phenyl]-3-Oxo-Androst-4-Ene-17-Carboxamide is a high-purity, non-steroidal synthetic steroid derivative characterized by its unique trifluoromethylphenyl substitution. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate or active pharmaceutical ingredient (API) in novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on endocrinology, oncology, and metabolic disorder research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroid-based drug candidates targeting hormone receptors.
• Biochemical Research: Used as a reference standard or probe compound in studies of steroid hormone action, receptor binding affinity, and signal transduction pathways.
• Preclinical Development: Employed in the discovery and optimization phase for potential therapeutics in areas such as anti-inflammatory, anti-cancer, and metabolic disease applications.
• Fine Chemical Synthesis: Acts as a specialized starting material for the preparation of more complex, fluorinated steroid analogs with tailored biological properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	(17β)-n-[2,5-Bis(Trifluoromethyl)Phenyl]-3-Oxo-Androst-4-Ene-17-Carboxamide
CAS No.	164656-19-3
Molecular Formula	C29H31F6NO2
Molecular Weight	539.56 g/mol
Synonyms	17β-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxoandrost-4-ene-17-carboxamide; BMS-564929; Androst-4-ene-17-carboxamide, 17β-N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-; (17β)-17-[[[2,5-Bis(trifluoromethyl)phenyl]amino]carbonyl]-3-oxoandrost-4-ene; Non-steroidal selective androgen receptor modulator (SARM) precursor; Fluorinated steroid carboxamide.
EINECS	Contact for details

Quality Control

Our (17β)-n-[2,5-Bis(Trifluoromethyl)Phenyl]-3-Oxo-Androst-4-Ene-17-Carboxamide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.