Description

2-Amino-4-(3,4-dimethoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the chromene class of heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex chromene-based molecular frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.
• Academic Research: Utilized in universities and R&D labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2-Amino-4-(3,4-dimethoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
CAS No.	164410-72-4
Molecular Formula	C20H22N2O4
Molecular Weight	354.40 g/mol
Synonyms	2-Amino-4-(3,4-dimethoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-1-benzopyran-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-(3,4-dimethoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-; 2-Amino-7,7-dimethyl-4-(3,4-dimethoxyphenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; Chromene-3-carbonitrile derivative; Tetrahydrochromene carbonitrile intermediate
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(3,4-dimethoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.