Description

1,3-Cyclobutanedicarboxylicacid,1-Amino-(9Ci) is a specialized, high-purity organic building block of significant interest in advanced synthetic chemistry. This compound matters for its role as a key chiral intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. Pharmaceutical R&D teams and fine chemical manufacturers need this material for constructing complex molecular architectures, particularly in the synthesis of constrained analogs and bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging its constrained cyclobutane ring structure.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique thermal or mechanical properties.
• Peptidomimetics: Integral for constructing conformationally restricted peptide analogs in medicinal chemistry programs.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in both university and corporate research laboratories.

Basic Information

Product Name	1,3-Cyclobutanedicarboxylicacid,1-Amino-(9Ci)
CAS No.	164225-42-7
Molecular Formula	C7H9NO4
Molecular Weight	171.15 g/mol
Synonyms	1-Amino-1,3-cyclobutanedicarboxylic acid; (1-Aminocyclobutane-1,3-dicarboxylic acid); 1,3-Cyclobutanedicarboxylic acid, 1-amino-; ACBD; 1-Amino-CBD; 1-Aminocyclobutane-1,3-dicarboxylic Acid; 164225-42-7; 1-Amino-1,3-cyclobutane dicarboxylate
EINECS	Contact for details

Quality Control

Our 1,3-Cyclobutanedicarboxylicacid,1-Amino-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.