Description

4-Amino-2,3-Difluoro-Phenol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both amino and phenolic functional groups on a difluorinated benzene ring, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for applications requiring precise molecular modification.

Application

• Key synthetic intermediate in the development of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Building block for advanced agrochemicals, such as herbicides and pesticides, where fluorine atoms enhance biological activity and stability.
• Precursor in the synthesis of functional dyes, pigments, and liquid crystal materials for electronic displays.
• Starting material for the production of specialized polymers and resins with enhanced thermal or chemical resistance.
• Intermediate in organic light-emitting diode (OLED) and other electronic material research.
• Used in academic and industrial research for exploring new fluorination chemistry and reaction pathways.

Basic Information

Product Name	4-Amino-2,3-Difluoro-Phenol
CAS No.	163733-99-1
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2,3-Difluoro-4-aminophenol; 4-Amino-2,3-difluorophenol; 4-Amino-2,3-difluoro-1-hydroxybenzene; 2,3-Difluoro-4-hydroxyaniline; 4-Hydroxy-2,3-difluoroaniline; Phenol, 4-amino-2,3-difluoro-; 1-Hydroxy-4-amino-2,3-difluorobenzene
EINECS	Contact for details

Quality Control

Our 4-Amino-2,3-Difluoro-Phenol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.