Description

2-Methyl-2-Trifluoromethylcyclohexanone is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group on a cyclohexanone ring, makes it a valuable precursor for creating molecules with enhanced metabolic stability and lipophilicity. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those requiring fluorinated motifs to modulate bioavailability and binding affinity.
• Agrochemical Synthesis: Serves as a building block in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Advanced Material Research: Used in the development of specialty polymers and liquid crystals, where its fluorinated structure can influence material properties like chemical resistance and dielectric constant.
• Organic Synthesis & Method Development: Employed in academic and industrial R&D labs to explore novel fluorination reactions and ring transformation chemistry.
• Flavor & Fragrance Chemistry: Acts as a potential intermediate for synthesizing complex, high-value aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	2-Methyl-2-Trifluoromethylcyclohexanone
CAS No.	163615-17-6
Molecular Formula	C8H11F3O
Molecular Weight	180.17 g/mol
Synonyms	2-(Trifluoromethyl)-2-methylcyclohexanone; 2-Methyl-2-(trifluoromethyl)cyclohexan-1-one; α,α,α-Trifluoro-2-methylcyclohexyl methyl ketone; 2-Methyl-α,α,α-trifluorocyclohexanemethyl ketone; 2-Trifluoromethyl-2-methylcyclohexanone; 1-Cyclohexyl-1,1,1-trifluoro-2-propanone (tautomeric form); TFMCyH; 2-Methyl-2-TFMCH
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-2-Trifluoromethylcyclohexanone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (g/mL at 20°C)	1.15 - 1.25

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.