Description

Bicyclo[4.2.0]Octa-1,3,5-Triene-7-Carboxylic Acid, (-)- (9Ci) is a high-purity, chiral bicyclic carboxylic acid derivative, serving as a sophisticated building block in advanced organic synthesis. Its unique strained ring structure and defined stereochemistry make it a valuable intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring complex, strained-ring pharmacophores.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific enantiomer can influence biological activity.
• Material Science Research: Serves as a precursor for novel organic materials, including specialty polymers and liquid crystals, leveraging its rigid, conjugated structure.
• Asymmetric Catalysis Ligand Precursor: Provides a scaffold for developing new chiral ligands and catalysts used in enantioselective synthesis.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry, exploring new cycloaddition and functionalization reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, complex specialty chemicals for various technological applications.

Basic Information

Product Name	Bicyclo[4.2.0]Octa-1,3,5-Triene-7-Carboxylic Acid, (-)- (9Ci)
CAS No.	163222-90-0
Molecular Formula	C9H8O2
Molecular Weight	148.16 g/mol
Synonyms	(-)-Bicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid; 7-Bicyclo[4.2.0]octa-1,3,5-trienecarboxylic acid, (-)-; (1S,6R)-Bicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid; 7-Carboxybicyclo[4.2.0]octa-1,3,5-triene; Chiral bicyclic carboxylic acid; Bicyclo[4.2.0]octatriene-7-carboxylic acid enantiomer.
EINECS	Contact for details

Quality Control

Our Bicyclo[4.2.0]Octa-1,3,5-Triene-7-Carboxylic Acid, (-)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, chemical assay, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its carboxylic acid nature and sensitivity, the container should be kept away from strong bases, oxidizing agents, and sources of heat. For long-term storage, consider inert atmosphere protection to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.