Description

Sulfosuccinimidyl Myristate Sodium is a specialized, water-soluble, amine-reactive ester commonly used as a bioconjugation reagent. This compound is critical for introducing myristoyl groups into biomolecules, facilitating studies on protein lipidation, membrane anchoring, and the creation of hydrophobic drug delivery systems. It is an essential tool for researchers and manufacturers in the fields of biopharmaceutical development, proteomics, and advanced material science.

Application

• Protein Lipidation & Modification: Covalently attaches myristic acid chains to peptides or proteins for studying membrane association and trafficking.
• Bioconjugation & Crosslinking: Serves as a homobifunctional crosslinker for conjugating amine-containing molecules, such as antibodies, enzymes, or polymers.
• Drug Delivery System Development: Used to synthesize prodrugs or to hydrophobically modify carriers like nanoparticles or liposomes to enhance cellular uptake.
• Biomaterial Functionalization: Modifies surfaces of biomaterials (e.g., hydrogels, chips) with myristoyl groups to control cell adhesion or protein binding.
• Diagnostic Reagent Synthesis: Employed in the preparation of labeled probes and reagents for immunoassays and diagnostic kits.
• Academic & Industrial Research: A key reagent in biochemical research for investigating lipidated protein function and signal transduction pathways.

Basic Information

Product Name	Sulfosuccinimidyl Myristate Sodium
CAS No.	162823-01-0
Molecular Formula	C18H28NNaO7S
Molecular Weight	425.48 g/mol
Synonyms	Sodium myristoyl sulfosuccinimidyl ester; Myristic acid sulfo-NHS ester sodium salt; N-Myristoyloxysulfosuccinimide sodium salt; Sulfo-NHS-myristate; Myristoyl-Sulfo-NHS; 2,5-Dioxopyrrolidin-1-yl 14-methyl-13-oxo-3,6,9,12-tetraoxa-2-azatetradecan-1-oate 1-sodium salt; N-Hydroxysulfosuccinimidyl myristate sodium salt; Sulfo-N-hydroxysuccinimidyl myristate
EINECS	Contact for details

Quality Control

Our Sulfosuccinimidyl Myristate Sodium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for sensitive bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.