Description

1,2-Ethanediamine, 1,2-Bis(4-Methylphenyl)-, Hydrochloride (1:2), (1S,2S)- is a high-purity, chiral diamine derivative supplied as a dihydrochloride salt. This compound is valued for its role as a sophisticated chiral building block and ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring specific (1S,2S) stereochemistry.
• Asymmetric Catalyst Ligand: Serves as a ligand for transition metal catalysts used in enantioselective hydrogenation, coupling, and other catalytic reactions.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals where stereochemistry is critical.
• Academic & Industrial Research: A valuable tool for chemists exploring new methodologies in organic synthesis and catalysis.
• Material Science: Potential monomer or cross-linking agent in the development of chiral polymers and advanced functional materials.

Basic Information

Product Name	1,2-Ethanediamine, 1,2-Bis(4-Methylphenyl)-, Hydrochloride (1:2), (1S,2S)-
CAS No.	162490-70-2
Molecular Formula	C₁₆H₂₂N₂ • 2HCl
Molecular Weight	323.28 g/mol (free base: 250.36 g/mol)
Synonyms	(1S,2S)-1,2-Bis(4-methylphenyl)ethylenediamine Dihydrochloride; (1S,2S)-N,N'-Bis(4-methylphenyl)ethylenediamine Dihydrochloride; (1S,2S)-1,2-Di-p-tolylethylenediamine Dihydrochloride; (S,S)-DPEN Dihydrochloride (p-Tolyl variant); (1S,2S)-DPEN•2HCl (p-Me); Chiral Diamine Ligand Salt; (S,S)-1,2-Bis(4-Methylphenyl)-1,2-ethanediamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our production of (1S,2S)-1,2-Bis(4-methylphenyl)ethylenediamine Dihydrochloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity (enantiomeric excess), and impurity profile is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.