Description

[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-Ferrocene is a chiral ferrocene-based oxazoline ligand, a highly specialized organometallic compound. This product matters for its critical role as an asymmetric catalyst or ligand in advanced organic synthesis, enabling the production of enantiomerically pure compounds. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, stereoselective building blocks for complex molecule synthesis.

Application

• As a chiral ligand in asymmetric catalysis, particularly for C-C and C-H bond-forming reactions.
• Key intermediate in the synthesis of novel pharmaceutical active ingredients (APIs) requiring specific stereochemistry.
• Research and development of new catalytic systems for enantioselective synthesis in academic and industrial laboratories.
• Production of specialty agrochemicals and flavors & fragrances where optical purity is critical.
• Component in the manufacture of advanced materials, such as chiral polymers or sensors.
• Use in methodological studies for developing new asymmetric transformations in organic chemistry.

Basic Information

Product Name	[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-Ferrocene
CAS No.	162157-04-2
Molecular Formula	C19H17FeNO
Molecular Weight	331.19 g/mol
Synonyms	(S)-4-Phenyl-4,5-dihydro-2-ferrocenyloxazole; (S)-2-Ferrocenyl-4-phenyl-4,5-dihydrooxazole; (S)-4-Phenyl-2-ferrocenyl-2-oxazoline; (S)-PPFO; (S)-Ferrocenyloxazoline; (S)-FcPHOX; (4S)-4-Phenyl-4,5-dihydro-2-(ferrocen-1-yl)-1,3-oxazole; (S)-2-(Ferrocenyl)-4-phenyl-4,5-dihydrooxazole
EINECS	Contact for details

Quality Control

Our [(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-Ferrocene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent potential oxidation and ensure long-term stability.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (ee)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.