Description

(S)-(4-Isopropyloxazolin-2-Yl)Ferrocene is a chiral ferrocene-based ligand, a sophisticated organometallic compound that combines the robust, planar aromaticity of ferrocene with a stereogenic oxazoline moiety. This structural synergy makes it an exceptionally valuable and versatile catalyst or ligand in asymmetric synthesis, where it imparts high enantioselectivity and reaction efficiency. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel synthetic routes to chiral active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric transformations, such as hydrogenation, allylic substitution, and cyclopropanation reactions.
• Key component in the synthesis of enantiomerically pure pharmaceuticals and bioactive molecules.
• Utilized in the development of novel agrochemicals requiring specific stereochemistry for optimal activity.
• Research tool in academic and industrial laboratories for methodological development in organometallic and asymmetric catalysis.
• Potential use in material science for creating chiral molecular frameworks and polymers.
• Intermediate in the preparation of more complex ferrocenyl ligands and catalysts.

Basic Information

Product Name	(S)-(4-Isopropyloxazolin-2-Yl)Ferrocene
CAS No.	162157-03-1
Molecular Formula	C16H19FeNO
Molecular Weight	297.18 g/mol
Synonyms	(S)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)ferrocene; (S)-4-Isopropyl-2-ferrocenyl-4,5-dihydrooxazole; (S)-2-Ferrocenyl-4-isopropyl-2-oxazoline; (S)-Josiphos-type ligand precursor; Ferrocenyloxazoline ligand; Chiral ferrocene oxazoline
EINECS	Contact for details

Quality Control

Our (S)-(4-Isopropyloxazolin-2-Yl)Ferrocene is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity, which is critical for reproducible catalytic performance. Each lot is characterized by modern analytical techniques including NMR, HPLC, and chiral analysis to confirm identity, chemical purity, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized; prolonged exposure to air should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	Orange to red crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.