Description

4-(Bromomethyl)-7-Hydroxy-Chromen-2-One is a versatile brominated coumarin derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a reactive bromomethyl group and a phenolic hydroxyl, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or possessing fluorescent properties for bio-imaging.
• Organic Synthesis Building Block: Used in coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions to introduce the coumarin scaffold into more complex molecules.
• Fluorescent Probe Development: Serves as a core structure for creating sensitive chemosensors and biological labels due to the inherent fluorescence of the coumarin moiety.
• Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs) and photostable polymers.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with enhanced biological activity.

Basic Information

Product Name	4-(Bromomethyl)-7-Hydroxy-Chromen-2-One
CAS No.	161798-25-0
Molecular Formula	C10H7BrO3
Molecular Weight	255.07 g/mol
Synonyms	7-Hydroxy-4-(bromomethyl)-2H-chromen-2-one; 4-Bromomethyl-7-hydroxycoumarin; 7-Hydroxy-4-bromomethylcoumarin; 4-(Bromomethyl)-7-hydroxy-2H-1-benzopyran-2-one; 4-Bromomethylumbelliferone; BMHC
EINECS	Contact for details

Quality Control

Our production of 4-(Bromomethyl)-7-Hydroxy-Chromen-2-One adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.