Description

n-tert-Butyl-2,4,6-trimethylbenzenesulfonamide, 97% is a high-purity, sterically hindered sulfonamide derivative, serving as a versatile synthetic intermediate and protecting group reagent in advanced organic synthesis. Its primary value lies in its ability to modulate reactivity and selectivity in complex chemical transformations, particularly in the development of pharmaceuticals and specialty materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring sterically hindered sulfonamide motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its structural features can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor or auxiliary ligand in the design of organometallic catalysts for asymmetric synthesis and polymerization reactions.
• Polymer Science: Employed as a monomer or modifier in the synthesis of specialty polymers, such as polyamides or sulfonated polymers with unique thermal or solubility properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.
• Protecting Group Chemistry: Acts as a robust amine-protecting group in multi-step synthetic sequences due to the stability of the tert-butylsulfonamide moiety.

Basic Information

Product Name	n-tert-Butyl-2,4,6-trimethylbenzenesulfonamide, 97%
CAS No.	161452-12-6
Molecular Formula	C₁₃H₂₁NO₂S
Molecular Weight	255.38 g/mol
Synonyms	N-(tert-Butyl)-2,4,6-trimethylbenzenesulfonamide; 2,4,6-Trimethyl-N-(2-methyl-2-propanyl)benzenesulfonamide; N-tert-Butyl-mesitylenesulfonamide; TBMSA; Mesitylenesulfonamide, N-tert-butyl-; N-(1,1-Dimethylethyl)-2,4,6-trimethylbenzenesulfonamide; tert-Butyl mesitylenesulfonamide
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-2,4,6-trimethylbenzenesulfonamide, 97% is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the specified 97% minimum purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.