Description

2H-1,2-Oxazine-3-Carboxylicacid,6-Ethoxytetrahydro-,Ethylester,(3R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Synthesis: Employed as a building block in catalytic asymmetric reactions to introduce the oxazine moiety into target molecules.
• Medicinal Chemistry: Utilized in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of manufacturing routes for complex molecules.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and the discovery of new bioactive compounds.

Basic Information

Product Name	2H-1,2-Oxazine-3-Carboxylicacid,6-Ethoxytetrahydro-,Ethylester,(3R,6R)-Rel-(9Ci)
CAS No.	161362-40-9
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	(3R,6R)-6-Ethoxy-1,2-oxazine-3-carboxylic acid ethyl ester; Ethyl (3R,6R)-6-ethoxytetrahydro-2H-1,2-oxazine-3-carboxylate; rel-(3R,6R)-Ethyl 6-ethoxytetrahydro-2H-1,2-oxazine-3-carboxylate; 2H-1,2-Oxazine-3-carboxylic acid, 6-ethoxytetrahydro-, ethyl ester, (3R,6R)-rel-; 6-Ethoxytetrahydro-2H-1,2-oxazine-3-carboxylic Acid Ethyl Ester (rel-(3R,6R)-form); Chiral Oxazine Ester; (3R,6R)-rel-6-Ethoxy-3-(ethoxycarbonyl)tetrahydro-2H-1,2-oxazine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide high-purity material suitable for research and development applications, with typical purity levels exceeding 95% (by HPLC). Each batch is characterized by Chiral HPLC to confirm stereochemical purity and identity. Certificates of Analysis (COA) containing detailed analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.