Description

2-Propanone, 1-(Tetrahydro-2-Furanyl)-, (S)- (9Ci) is a chiral ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, where its defined stereochemistry is crucial for efficacy. Pharmaceutical, agrochemical, and fine chemical research and development teams need this high-purity intermediate to create novel active ingredients and functional materials with precision.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced, stereospecific pesticides and herbicides where the (S)-enantiomer imparts specific biological activity.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor for chiral ligands and catalysts used in enantioselective synthesis to produce other high-value chiral compounds.
• Fine Chemical & Flavor/Fragrance Intermediate: Employed in the synthesis of complex natural product analogs and specialty aroma chemicals that require specific stereochemical configurations.
• Academic & Industrial R&D: A valuable tool for chemists in process development and methodological studies focused on stereocontrolled carbon-carbon bond formation.

Basic Information

Product Name	2-Propanone, 1-(Tetrahydro-2-Furanyl)-, (S)- (9Ci)
CAS No.	161040-21-7
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	(S)-1-(Tetrahydro-2-furanyl)-2-propanone; (S)-1-(Tetrahydrofuran-2-yl)propan-2-one; (S)-1-(Oxolan-2-yl)propan-2-one; (S)-2-Propanone, 1-(tetrahydro-2-furanyl)-; (S)-Tetrahydrofurfuryl acetone; (S)-THFA acetone; (S)-1-(2-Tetrahydrofuryl)-2-propanone; (S)-α-Acetyl tetrahydrofurfuryl alcohol precursor
EINECS	Contact for details

Quality Control

Our production of 2-Propanone, 1-(Tetrahydro-2-Furanyl)-, (S)- (9Ci) CAS 161040-21-7 adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. All materials undergo comprehensive analytical testing, including chiral HPLC, GC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.