Description

Dmg-Peg 2000 is a high-purity, functionalized polyethylene glycol derivative, identified by CAS No. 160743-62-4. This compound is a critical intermediate and linker molecule, valued for its ability to impart water solubility, biocompatibility, and stealth properties to various constructs. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who are developing advanced drug delivery systems, bioconjugates, and diagnostic agents.

Application

• Pharmaceutical Linker: Used for the conjugation of active pharmaceutical ingredients (APIs), peptides, or proteins to create prodrugs or targeted therapies.
• PEGylation Reagent: Serves as a key material for PEGylating therapeutic proteins and peptides to enhance their circulating half-life and reduce immunogenicity.
• Bioconjugation Chemistry: Acts as a heterobifunctional crosslinker for attaching dyes, labels, or other molecules to antibodies, oligonucleotides, or nanoparticles.
• Drug Delivery System Development: Incorporated into the synthesis of micelles, liposomes, and polymer-drug conjugates to improve solubility and pharmacokinetic profiles.
• Diagnostic Agent Formulation: Utilized in the preparation of contrast agents and molecular imaging probes for enhanced biocompatibility.
• Biomaterial Modification: Applied to surface functionalization of medical devices and implants to improve hydrophilicity and reduce protein adsorption.

Basic Information

Product Name	Dmg-Peg 2000
CAS No.	160743-62-4
Molecular Formula	Contact for details
Molecular Weight	~2000 g/mol (nominal)
Synonyms	DMG-PEG2000; 1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol 2000; DMG-PEG2000; PEG2000-DMG; (Rac)-DMG-PEG2000; 1,2-Ditetradecanoyl-rac-glycerol, methoxypolyethylene glycol ester; Lipid-PEG conjugate
EINECS	Contact for details

Quality Control

Our Dmg-Peg 2000 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and tests for critical impurities such as residual solvents and heavy metals. We provide comprehensive Certificates of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Molecular Weight (GPC)	1900 - 2100 Da
DMG Content	Conforms
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.