Description

4-(Toluene-4-Sulfonyloxymethyl)-Piperidine-1-Carboxylic Acid Benzyl Ester, 98 % is a high-purity, advanced pharmaceutical intermediate with a defined molecular architecture. This compound is valued for its role as a key synthetic building block in the development of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those containing piperidine scaffolds.
• Protease Inhibitor Research: Used in the research and development of protease inhibitors due to its sulfonyloxy and ester functional groups.
• Peptidomimetic Chemistry: Serves as a precursor in the construction of peptidomimetics and other bioactive compounds.
• Medicinal Chemistry R&D: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Custom Synthesis: Utilized by fine chemical manufacturers for contract synthesis and the production of specialized, high-value compounds.
• Chemical Biology Probes: Can be used to develop molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	4-(Toluene-4-Sulfonyloxymethyl)-Piperidine-1-Carboxylic Acid Benzyl Ester, 98 %
CAS No.	160586-68-5
Molecular Formula	C21H25NO5S
Molecular Weight	403.49 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-[[(4-methylphenyl)sulfonyl]oxy]methyl]piperidine; 4-[(p-Toluenesulfonyloxy)methyl]-1-carbobenzoxypiperidine; 1-CBZ-4-(p-Toluenesulfonyloxymethyl)piperidine; 4-(Tosyloxymethyl)-1-N-CBZ-piperidine; 1-N-CBZ-4-(p-Toluenesulfonyloxymethyl)piperidine; 4-[(4-Methylbenzenesulfonyl)oxy]methyl]-1-piperidinecarboxylic acid benzyl ester; Benzyl 4-[[(4-methylphenyl)sulfonyl]oxy]methyl]piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 4-(Toluene-4-Sulfonyloxymethyl)-Piperidine-1-Carboxylic Acid Benzyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is tested against comprehensive specifications, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0 %
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.